So the film's intro, with its predictable dialogue drowning in the overly sentimental score, doesn't bode well. But something wondrous happens. As soon as their hogs hit the highway, the movie becomes consistently funny. There's still gross-out slapstick, homophobic gags and even some nudity (and when Macy's involved, combinations of all three), but the camaraderie between the four leads is fantastic. It doesn't necessarily elevate the lowbrow material—it makes you enjoy the actors so much that you laugh in spite of the material.
There are some impressive supporting players: Ray Liotta as the leader of a real biker gang, Marisa Tomei as Macy's love interest and a surprise cameo that saves what would have been an unsatisfying ending.
Older audiences will sympathize with the aging actors, younger ones will chuckle at the slapstick, and film snobs will be reminded that you can't rule out a movie just because it has a bad trailer and a tired premise.